![A distinctive nuclear morphology in acute myeloid leukemia is strongly associated with loss of HLA-DR expression and FLT3 internal tandem duplication | Leukemia A distinctive nuclear morphology in acute myeloid leukemia is strongly associated with loss of HLA-DR expression and FLT3 internal tandem duplication | Leukemia](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fsj.leu.2403458/MediaObjects/41375_2004_Article_BF2403458_Fig1_HTML.jpg)
A distinctive nuclear morphology in acute myeloid leukemia is strongly associated with loss of HLA-DR expression and FLT3 internal tandem duplication | Leukemia
![John Libbey Eurotext - Hématologie - Caractéristiques biologiques des LAM à cup-like nuclei, une entité rare associée à une mutation de NPM1 et de FLT3 : confusion diagnostique possible avec une leucémie John Libbey Eurotext - Hématologie - Caractéristiques biologiques des LAM à cup-like nuclei, une entité rare associée à une mutation de NPM1 et de FLT3 : confusion diagnostique possible avec une leucémie](https://www.jle.com/e-docs/00/04/8B/8D/texte_alt_jlehma0826gr1.jpg)
John Libbey Eurotext - Hématologie - Caractéristiques biologiques des LAM à cup-like nuclei, une entité rare associée à une mutation de NPM1 et de FLT3 : confusion diagnostique possible avec une leucémie
![PDF] Association of “cup-like” blasts morphology with NPM1 mutation in acute myeloid leukemia | Semantic Scholar PDF] Association of “cup-like” blasts morphology with NPM1 mutation in acute myeloid leukemia | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/bd3dcc2a78cfa7daa2e1e2f9602bcd55436c8772/2-Figure1-1.png)
PDF] Association of “cup-like” blasts morphology with NPM1 mutation in acute myeloid leukemia | Semantic Scholar
![Acute myeloid leukemia with cuplike nuclei and intracytoplasmic inclusions following myelodysplastic syndrome | SpringerLink Acute myeloid leukemia with cuplike nuclei and intracytoplasmic inclusions following myelodysplastic syndrome | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs12185-009-0362-x/MediaObjects/12185_2009_362_Fig1_HTML.jpg)
Acute myeloid leukemia with cuplike nuclei and intracytoplasmic inclusions following myelodysplastic syndrome | SpringerLink
![Kyle Bradley, MD on X: "Cup-like blasts in AML. Associated with normal karyotype, FLT3 and/or NPM1 mutations, and HLA-DR-/CD34- by flow (flow ddx = APL). https://t.co/8vMp8zLNuR" / X Kyle Bradley, MD on X: "Cup-like blasts in AML. Associated with normal karyotype, FLT3 and/or NPM1 mutations, and HLA-DR-/CD34- by flow (flow ddx = APL). https://t.co/8vMp8zLNuR" / X](https://pbs.twimg.com/media/CufMf9HXgAA5oP3.jpg)
Kyle Bradley, MD on X: "Cup-like blasts in AML. Associated with normal karyotype, FLT3 and/or NPM1 mutations, and HLA-DR-/CD34- by flow (flow ddx = APL). https://t.co/8vMp8zLNuR" / X
![Blood Academy on X: "NPM1‐mutated acute myeloid leukemia 🔷blast cells with nuclear indentation 🔷when seen in profile = cup‐like shape 🔷seen from above = giant nucleolus 🔷also note the Auer rods and Blood Academy on X: "NPM1‐mutated acute myeloid leukemia 🔷blast cells with nuclear indentation 🔷when seen in profile = cup‐like shape 🔷seen from above = giant nucleolus 🔷also note the Auer rods and](https://pbs.twimg.com/media/ERm6quEXUAYH5rs.jpg)
Blood Academy on X: "NPM1‐mutated acute myeloid leukemia 🔷blast cells with nuclear indentation 🔷when seen in profile = cup‐like shape 🔷seen from above = giant nucleolus 🔷also note the Auer rods and
![Association of cup-like nuclei in blasts with FLT3 and NPM1 mutations in acute myeloid leukemia | SpringerLink Association of cup-like nuclei in blasts with FLT3 and NPM1 mutations in acute myeloid leukemia | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs00277-012-1645-5/MediaObjects/277_2012_1645_Fig2_HTML.gif)
Association of cup-like nuclei in blasts with FLT3 and NPM1 mutations in acute myeloid leukemia | SpringerLink
![A case of cup‐like blasts associated with B‐lymphoblastic leukemia without NPM1 and FLT3 internal tandem duplication mutations - Rieu - 2020 - eJHaem - Wiley Online Library A case of cup‐like blasts associated with B‐lymphoblastic leukemia without NPM1 and FLT3 internal tandem duplication mutations - Rieu - 2020 - eJHaem - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/7b297ac7-25dd-45ac-b39a-3ad48828b671/jha291-fig-0001-m.jpg)